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UK Scientists Make Breakthrough To Kill ‘Unkillable’ Cancer Cells

UK Scientists Make Breakthrough To Kill ‘Unkillable’ Cancer Cells

The scientists are based at the University of Dundee.

Stewart Perrie

Stewart Perrie

Researchers from Scotland have been looking at the diseases that don't respond to any type of medicine.

These are dubbed 'undruggable proteins' that cause illnesses like cancer and Huntingdon's disease.

But the scientists at the University of Dundee have found how to target these proteins by using molecules to bind them to neutralising agents, and they've called this reaction the 'kiss of death'.

Professor Alessio Ciulli told The Sun: "Crucially, we have found that it is not enough for this neutralising protein to sit close to the bad protein.

"It has to make direct contact with it, to 'kiss' it and not just a little peck, but a real 'Gone with the Wind' embrace."

bacteria 2
bacteria 2

Credit: PA Images

They say they've been aware of the proteins that cause disease, but being able to fight them and break them down has been a battle that has bugged scientists for years.

Professor Ciulli says: "The major problem is that we have been unable to find the small molecules which can successfully bind to these proteins and at the same time hamper their function.

"It is a highly complex area as these proteins can often fool regulators within the cell and be extremely difficult to pin down with inhibitors."

He says this is just a start in overcoming the devastating effects these proteins can have on the body - but it's certainly a step in the right direction.

It's thought pharmaceutical companies will use this information to develop more of these neutralising agents to attack the bad proteins.

Source: The Sun

Featured Image Credit: PA Images

Topics: Cancer